Publication & Patent

Publications

1. Articles

  • 32. Rae Hyung Kang, Morteza Rasoulianboroujeni, Maryam Kianpour, Lauren Repp, Suzanne M. Ponik, and Glen S. Kwon*, Ratiometric drug delivery, under revision
  • 31. Su Hyeon Cho, Morteza Rasoulianboroujeni, Rae Hyung Kang,* (corresponding author) and Glen S. Kwon*, From Conventional to Next-Generation Strategies: Recent Advances in Polymeric Micelle Preparation for Drug Delivery, Pharmaceutics. 2025, accepted
  • 30. Morteza Rasoulianboroujeni, Rae Hyung Kang (co-first author), Maraya Klukas, Glen S Kwon, Crystallization of supersaturated PEG-b-PLA for the production of drug-loaded polymeric micelles, J. Control. Release. 2025, 380, 457–468.
  • 29. Rae Hyung Kang*, Seung Woo Baek, Chang-Kyu Oh, Yun Hak Kim, and Dokyoung Kim, Recent Advances of Macrostructural Porous Silicon for Biomedical Applications, ACS Appl. Mater. Interfaces. 2025, 17, 4, 5609–5626.
  • 28. Hyeji Um, Rae Hyung Kang (co-first author), Jaehoon Kim, Eun Woo Seo, Jinwoo Ahn, Jucheol Lee, and Dokyoung Kim, An in-depth investigation of the C2 polymer as a next-generation transdermal drug delivery platform, Polymer, 2023, 283, 126271.
  • 27. Hyeji Um, Rae Hyung Kang (co-first author), and Dokyoung Kim, Iron-silicate-coated porous silicon nanoparticles for in situ ROS self-generation, Colloids Surf. B. 2023, 225, 113273.
  • 26. Ji Hyeon Oh, Hye ji Um, Yoon Kyung Park, Eun-Kyoung Bang, Rae Hyung Kang* (corresponding author) and Dokyoung Kim, Porous silicon surface modification via a microwave-induced in situ cyclic disulfide (S-S) cleavage and Si-S bond formation, Colloids Surf. B. 2023, 222, 113055.
  • 25. Rae Hyung Kang, Kyung Oh Jung, and Dokyoung Kim, Self-Sealing Chemistry of Calcium/Magnesium Silicate on Porous Silicon Nanoparticles for Enhanced Drug-loading and Slowed Drug-releasing, Mater. Lett. 2022, 324, 1, 132719.
  • 24. Yoon Kyung Park, Paramesh Jangili, Soyu Zi, Rae Hyung Kang* (corresponding author) Dokyoung Kim, and Jong Seung Kim, SIWV tetrapeptide and ROS-responsive prodrug conjugate for advanced glioblastoma therapy, Chem. Commun. 2022, 58, 10941–10944.
  • 23. Jaehoon Kim, Jong Min An, Youngwoong Kim, Ji Hye Jin, Sung Soo Kim, Rae Hyung Kang* (corresponding author) and Dokyoung Kim, TAMRA-conjugated DRL tripeptide for the visualization of synovium, Dyes Pigm. 2022, 205, 110590.
  • 22. Rae Hyung Kang, Na Hee Kim, and Dokyoung Kim, A Transformable and Biocompatible Polymer Series using Ring-opening Polymerization of Cyclic Silane for More Effective Transdermal Drug Delivery, Chem. Eng. J. 2022, 440, 135989.
  • 21. Rae Hyung Kang, Youngwoong Kim, Hye Ji Um, Jaehoon Kim, Eun-Kyoung Bang, Seung Geun Yeo, and Dokyoung Kim, Glioblastoma Homing Photodynamic Therapy Based on Multifunctionalized Porous Silicon Nanoparticles, ACS Appl. Nano Mater. 2022, 5, 4, 5387–5397.
  • 20. Na Hee Kim, Rae Hyung Kang, Peter Verwilst, and Dokyoung Kim, A fluorescent nanoprobe based on AIEgen: Visualization of silver ions and sensing applications in cancer cells and S. aureus, Dyes Pigm. 2022, 198, 110027.
  • 19. Na Hee Kim, Rae Hyung Kang (co-first author), and Dokyoung Kim, Pentafluoro-benzene functionalized AIEgen: A highly sensitive and fast responsive fluorescent nanoprobe for the detection of gold ions, Dyes Pigm. 2022, 198, 110007.
  • 18. Rae Hyung Kang and Dokyoung Kim, Thermally Induced Silane Dehydrocoupling: Hydrophobic and Oleophilic Filter Paper Preparation for Water Separation and Removal from Organic Solvents, Materials. 2021, 14, 5775.
  • 17. Rae Hyung Kang, Jinju Park, Jieun Kim, Tamrin Chowdhury, Ji Hyeon Oh, Jaehoon Kim, Jaeha Shin, Minji Kim, Chul-kee Park, Sungjun Lee, Ji Yeoun Lee, and Dokyoung Kim, A Deep Dive: SIWV Tetra-Peptide Enhancing the Penetration of Nanotherapeutics into the Glioblastoma, ACS Biomater. Sci. Eng. 2022, 8, 10, 4163–4174.
  • 16. Rae Hyung Kang, Yumi Kim, Ji Hyeon Kim, Na Hee Kim, Hyun Min Ko, Seung-Hyeon Lee, Inseob Shim, Jong Seung Kim, Hyeung-jin Jang, and Dokyoung Kim, Self-Activating Therapeutic Nanoparticle: A Targeted Tumor Therapy Using Reactive Oxygen Species Self-Generation and Switch-on Drug Release, ACS Appl. Mater. Interfaces 2021, 13, 30359–30372.
  • 15. Na Hee Kim, Byeong Wook Kim, Heechang Moon, Hajung Yoo, Rae Hyung Kang, Junho K Hur, Yohan Oh, B Moon Kim, and Dokyoung Kim, AIEgen-based nanoprobe for the ATP sensing and imaging in cancer cells and embryonic stem cells, Anal. Chim. Acta. 2021, 1152, 338269.
  • 14. Ji Hyeon Oh, Rae Hyung Kang (co-first author), Jaehoon Kim, Eun-Kyoung Bang, and Dokyoung Kim, Thermally induced silane dehydrocoupling on porous silicon nanoparticles for ultra-long-acting drug release, Nanoscale. 2021, 13, 15560–15568.
  • 13. Rae Hyung Kang, Jeong-Eun Jang, Eugene Huh, Seong Jae Kang, Dae-Ro Ahn, Jae Seung Kang, Michael J. Sailor, Seung Geun Yeo, Myung Sook Oh, Dokyoung Kim, and Hyo Young Kim, A Brain Tumor-homing Tetra-peptide Delivers a Nano-Therapeutic for More Effective Treatment of a Mouse Model of Glioblastoma, Nanoscale Horiz. 2020, 5, 1213–1225.
  • 12. Seo Hyeon Lee, Young Ho Choe, Rae Hyung Kang (co-first author), Yu Rim Kim, Na Hee Kim, Sangrim Kang, Youngseo Kim, Sungnam Park, Young-Min Hyun, and Dokyoung Kim, A bright blue fluorescent dextran for two-photon in vivo imaging of blood vessels, Bioorg. Chem. 2019, 89, 103019.
  • 11. Rae Hyung Kang, Seo Hyeon Lee, Sangrim Kang, Jinyoung Kang, Junho K. Hur, and Dokyoung Kim, Systematic Degradation Rate Analysis of Surface-Functionalized Porous Silicon Nanoparticles, Materials. 2019, 12, 580.
  • 10. Guk Young Ahn, Dong-Hyun Paik, Ki-Young Jeong, Seung-Woon Baek, Rae-Hyoung Kang, Eun Seong Lee, and Sung-Wook Choi, Electrosprayed Folic Acid-Conjugated Ursolic Acid Nanoparticles for Tumor Therapy, Macromol. Res. 2018, 26, 573–576.
  • 9. Seung Woon Baek, Seung-Kwan Moon, Rae Hyung Kang, Youngchang Ah, Hyuk Kim, and Sung-Wook Choi, One-Step Fabrication of Uniform Biodegradable Microbeads with Unimodal and Bimodal Porous Structures Using Spontaneous Microphase Separation, Macromol. Mater. Eng. 2018, 1800139.
  • 8. Rae-Hyung Kang, Seung Woon Baek, Tae-Kyung Ryu, and Sung-Wook Choi, Fabrication of blue-fluorescent nanodiamonds modified with alkylisocyanate for cellular bioimaging, Colloids Surf. B 2018, 167, 191–196.
  • 7. Tae-Kyung Ryu, Seung-Woon Baek, Rae-Hyung Kang, Ki-Young Jeong, Dae-Ryong Jun, and Sung-Wook Choi, Photodynamic and photothermal tumor therapy using phase-change material nanoparticles containing chlorin e6 and nanodiamonds, J. Control. Release. 2018, 270, 237–245.
  • 6. Dae-Ryong Jun, Yu Ri Choi, Rae Hyung Kang, and Sung-Wook Choi, Polydimethylsiloxane Fluidic Device with Polydopamine-Coated Inner Channel for Production of Uniform Droplets, Macromol. Mater. Eng. 2016, 301, 1044–1048.
  • 5. Tae-Kyung Ryu, Seung Woon Baek, Rae Hyung Kang, and Sung-Wook Choi, Selective Photothermal Tumor Therapy Using Nanodiamond-Based Nanoclusters with Folic Acid, Adv. Funct. Mater. 2016, 26, 6428–6436.
  • 4. Seok-Joon Hwang, Ji-Seon Lee, Tae-Kyung Ryu, Rae-Hyung Kang, Ki-Young Jeong, Dae-Ryong Jun, Jung-Min Koh, Sung-Eun Kim, and Sung-Wook Choi, Alendronate-Modified Hydroxyapatite Nanoparticles for Bone-Specific Dual Delivery of Drug and Bone Mineral, Macromol. Res. 2016, 24, 623–628.
  • 3. Tae-Kyung Ryu, Rae-Hyoung Kang, Ki-Young Jeong, Dae-Ryong Jun, Jung-Min Koh, Doyun Kim, Soo Kyung Bae, and Sung-Wook Choi, Bone-targeted delivery of nanodiamond-based drug carriers conjugated with alendronate for potential osteoporosis treatment, J. Control. Release. 2016, 232, 152–160.
  • 2. Dong-Hyun Paik, Hyunsuk Lee, Rae-Hyoung Gang, Yong-Jin Kim, John Hwan Lee, and Sung-Wook Choi, Preparation of Porous PMMA/TiO2 Microspheres by Spray Drying Process, J. Soc. Cosmet. Sci. Korea. 2016, 42, 1–7.
  • 1. Hyunsuk Lee, Dong-Hyun Paik, Ki-Young Jeong, Rae-Hyoung Gang, Johnhwan Lee, and Sung-Wook Choi, Fabrication of poly(methyl methacrylate) and TiO2 composite microspheres with controlled morphologies and porous structures by electrospraying, J. Mater. Sci. 2015, 50, 6531–6538.

2. Patent

  • 10. 알킬화합물 및 생분해성 고분자가 결합된 나노 다이아몬드 및 이의 제조 방법 (Nano diamond conjugated with alkyl compounds and biodegradable polymer) (KR 10-2591595)
  • 9. 활성산소종 유도 및 이로 인해 자가활성화되는 다공성 실리콘 나노입자 기반의 약물 전달체 및 이의 제조방법 (Porous silicon nanoparticle-based drug delivery system inducing reactive oxygen species and self-activation thereof, and method for preparing the same) (KR 10-2656698)
  • 8. 실리콘 고분자 화합물 및 이를 포함하는 경피 전달 시스템 (Silicone polymer compound and transdermal delivery system comprising the same) (KR 10-2023-0064523)
  • 7. 새로운 덱스트란 고분자 청색 형광체 (Novel blue fluorescent substance based on dextran polymer) (KR 10-2270784)
  • 6. 뇌암세포 표적용 펩타이드로 표면 개질된 약물 전달용 나노입자, 이의 제조방법 및 이의 용도 (Nanoparticles for drug delivery surface-modified with brain tumor cell targeting peptide, preparation method thereof and use thereof) (KR 10-2267519)
  • 5. 고분자 화합물 및 이를 포함하는 경피 전달용 조성물 (Polymer Compound and Composition for Transdermal Delivery Comprising the Same) (KR 10-2302164)
  • 4. Porous silicon nanoparticle-based drug delivery system inducing reactive oxygen species and self-activation thereof, and method for preparing same (US 17/739,616)
  • 3. Method of manufacturing micelles for drug delivery (US 18/122,661)
  • 2. Silicone polymer compound and transdermal delivery system comprising same (US 18/654,778)
  • 1. Nanoparticles for delivering drug, whose surface is modified with peptide for targeting brain cancer, preparation method thereof and use thereof (US 12/128,041).